Clinical and surgical profile of patients with sequelae of pulmonary tuberculosis who underwent thoracic surgery at a national hospital in Lima, Peru, 2017–2022
DOI:
https://doi.org/10.24265/horizmed.2025.v25n2.07Keywords:
Sequela, Tuberculosis, Pulmonary , Thoracic SurgeryAbstract
Objective: To describe the clinical and surgical profile of patients with sequelae of pulmonary tuberculosis (TB) who underwent thoracic surgery at Hospital Nacional Dos de Mayo between 2017 and 2022. Materials and methods: A descriptive and retrospective research involving patients
with sequelae of pulmonary TB who underwent thoracic surgery. Data were recorded using Excel
365, and descriptive statistical analysis was performed using IBM SPSS Statistics 26. Results: A
total of 31 medical records were reviewed. The mean age was 43.90 ± 16.185 years, with a male
predominance (61.30 %). Most patients came from Lima (54.80 %) and the Peruvian highlands
(41.90 %), and 29.00 % had completed secondary education. Harmful habits—alcohol and tobacco
use—were reported in 25.80 % (n = 8), and 16.10 % (n = 5) had diabetes mellitus. Regarding TB
history, 71.00 % (n = 22) of cases were newly diagnosed drug-susceptible TB (DS-TB), 19.40 %
(n = 6) were relapsed DS-TB and 9.70 % (n = 3) had multidrug-resistant (MDR) TB. Bronchiectasis
was the most common surgical indication (74.10 %, n = 23), followed by aspergilloma (61.20 %,
n = 19) and cavitation (19.30 %, n = 6). Lobectomy was the most frequently performed procedure (90.30 %, n = 28), primarily in the right upper lobe. Postoperative complications included surgical site infection (16.10 %, n = 5), bronchopleural fistula (6.50 %, n = 2) and retained hemothorax (3.20 %, n = 1). Conclusions: The clinical and surgical profile of patients with sequelae of pulmonary TB who underwent thoracic surgery at Hospital Nacional Dos de Mayo is characterized by adult males with completed secondary education, mainly from Lima and the Peruvian highlands. Most cases were newly diagnosed and relapsed DS-TB. Bronchiectasis and aspergilloma were the most common surgical indications, with lobectomy being the most frequent surgical procedure. No postoperative deaths were reported.
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References
Dravniece G, Cain KP, Holtz TH, Riekstina V, Leimane V, Zaleskis R.
Adjunctive resectional lung surgery for extensively drug-resistant
tuberculosis. Eur Respir J [Internet]. 2009;34(1):180-3. Disponible en:
https://doi.org/10.1183/09031936.00047208
Somocurcio JG, Sotomayor A, Shin S, Portilla S, Valcárcel M, Guerra D,
et al. Tratamiento quirúrgico de la tuberculosis pulmonar multidrogo
resistente en el Perú: serie de 304 casos. Rev Peru Med Exp Salud Publica
[Internet]. 2009;26(3):288-93. Disponible en: http://www.scielo.org.
pe/scielo.php?script=sci_arttext&pid=S1726-46342009000300004
Organización Panamericana de la Salud. Atención primaria de salud
[Internet]. Washington, D.C.: OPS; 2020. Disponible en: https://
www.paho.org/es/temas/atencion-primaria-salud
Organización Panamericana de la Salud. Tuberculosis [Internet].
Washington, D.C.: OPS; 2023. Disponible en: https://www.paho.org/
es/temas/tuberculosis
Ministerio de Salud del Perú. Boletín tuberculosis n.º 01 - agosto de
[Internet]. Lima: MINSA; 2022. Disponible en: https://www.
gob.pe/institucion/minsa/informes-publicaciones/3351010-boletintuberculosis-
n-01-agosto-de-2022
Centro Nacional de Epidemiología, Prevención y Control de
Enfermedades (CDC MINSA). Vigilancia de tuberculosis [Internet].
Lima: MINSA; 2023. Disponible en: https://www.dge.gob.pe/
portalnuevo/vigilancia-epidemiologica/vigilancia-de-tuberculosis/
Romero M, Romero S, Sánchez J, Santamaria-Alza Y, Mendoza T, Bolivar
F. Secuelas estructurales y funcionales de tuberculosis pulmonar: una
revisión de tema. Rev Am Med Respir [Internet]. 2016;16(2):163-9.
Disponible en: https://www.scielo.org.ar/scielo.php?script=sci_
arttext&pid=S1852-236X2016000200007
Machida K, Maekura R. State of the art: sequelae of tuberculosis.
Kekkaku [Internet]. 2005;80(10):655-74. Disponible en: https://
pubmed.ncbi.nlm.nih.gov/16296394/
Cereceda J, Samso C, Segura A, Sanhueza P. Bronquiectasias en
adultos: características clínicas experiencia de 5 años 1998-2003.
Rev Chil Enferm Respir [Internet]. 2005;21(3):171-8. Disponible en:
https://revchilenfermrespir.cl/index.php/RChER/article/view/653
Ocampo ML, Salmón JA, Noguera VD, Zabala OC. Bronquiectasias:
revisión bibliográfica. Rev Posgrado VIa Cátedra Med [Internet].
;182:16-9. Disponible en: http://med.unne.edu.ar:8080/
revistas/revista182/5_182.pdf
Fernández P, Jiménez P. Bronquiectasias: ¿no es más una enfermedad
huérfana? Rev Chil Enferm Respir [Internet]. 2016;32(3):169-77.
Disponible en: https://revchilenfermrespir.cl/index.php/RChER/
article/view/261
Romero S, Graziani D. Bronquiectasias. Medicine (Madr) [Internet].
;12(63):3691-8. Disponible en: https://doi.org/10.1016/j.
med.2018.09.010
World Health Organization. WHO consolidated guidelines on drugresistant
tuberculosis treatment [Internet]. Geneva: WHO; 2019.
Disponible en: https://apps.who.int/iris/handle/10665/311389
World Health Organization. The use of delamanid in the treatment of
multidrug-resistant tuberculosis: interim policy guidance [Internet].
Geneva: WHO; 2014. Disponible en: https://iris.who.int/bitstream/
handle/10665/137334/WHO_HTM_TB_2014.23_eng.pdf
Martínez de Salinas y Salcedo JL. Indicaciones actuales de la
cirugía en la tuberculosis pulmonar. Arch Bronconeumol [Internet].
;12(4):163-9. Disponible en: https://doi.org/10.1016/S0300-
(15)32714-9
Pomerantz BJ, Cleveland JC, Olson HK, Pomerantz M. Pulmonary
resection for multi-drug resistant tuberculosis. J Thorac Cardiovasc
Surg [Internet]. 2001;121(3):448-53. Disponible en: https://doi.
org/10.1067/mtc.2001.112339
Rizzi A, Rocco G, Robustellini M, Rossi G, Della Pona C, Massera F.
Results of surgical management of tuberculosis: experience in
patients undergoing operation. Ann Thorac Surg [Internet].
;59(4):896-900. Disponible en: https://doi.org/10.1016/0003-
(95)00011-9
Yablonskii P, Kudriashov G, Avetisyan A. Surgical resection in the
treatment of pulmonary tuberculosis. Thorac Surg Clin [Internet].
;29(1):37-46. Disponible en: https://doi.org/10.1016/j.
thorsurg.2018.09.003
Bertolaccini L, Viti A, Di Perri G, Terzi A. Surgical treatment of
pulmonary tuberculosis: the phoenix of thoracic surgery? J Thorac
Dis [Internet]. 2013;5(2):198-9. Disponible en: https://doi.
org/10.3978/j.issn.2072-1439.2012.03.18
Iseman MD, Madsen L, Goble M, Pomerantz M. Surgical intervention
in the treatment of pulmonary disease caused by drug-resistant
Mycobacterium tuberculosis. Am Rev Respir Dis [Internet].
;141(3):623-5. Disponible en: https://doi.org/10.1164/
ajrccm/141.3.623
Chávez JA. Tratamiento quirúrgico de la tuberculosis pulmonar
activa y sus formas secuelares en el Hospital Nacional Edgardo
Rebagliati M, enero 2005 - diciembre 2010 [Tesis de posgrado]. Lima:
Universidad Nacional Mayor de San Marcos; 2014. Disponible en:
https://unmsm.ent.sirsi.net/client/es_ES/all_libs/search/
detailnonmodal/ent:$002f$002fSD_ILS$002f0$002fSD_ILS:434570/one
Giller DB, Giller GV, Imagozhev YaG, Gadzhieva PG, Kesaev OS,
Koroev VV, et al. Surgical collapse in the treatment of single lung
tuberculosis. Khirurgiia (Mosk) [Internet]. 2021;1:15-21. Disponible
en: https://doi.org/10.17116/hirurgia202101115
Wang L, Xia F, Li F, Qian X, Zhu Y, Chen H, et al. Pulmonary resection
in the treatment of multidrug-resistant tuberculosis: a case series.
Medicine (Baltimore) [Internet]. 2017;96(50):e9109. Disponible en:
https://doi.org/10.1097/MD.0000000000009109
Duzhyĭ ID, Kravets’ OV, Hres’ko IIa. Possibilities of surgical treatment
for advanced multiresistant pulmonary tuberculosis. Klin Khir
[Internet]. 2014;(3):34-6. Disponible en: https://pubmed.ncbi.nlm.
nih.gov/25097997/
Man MA, Nicolau D. Surgical treatment to increase the success rate of
multidrug-resistant tuberculosis. Eur J Cardiothorac Surg [Internet].
;42(1):e9-12. Disponible en: https://doi.org/10.1093/ejcts/
ezs215
Chinchón LA. Cirugía de resección pulmonar como tratamiento
coadyuvante para la curación de los pacientes con TBC-MDR en el
Hospital Nacional Hipólito Unanue 2006-2010 [Tesis de posgrado]. Lima:
Universidad Nacional Mayor de San Marcos; 2012. Disponible en: https://
unmsm.ent.sirsi.net/client/es_ES/all_libs/search/detailnonmodal/
ent:$002f$002fSD_ILS$002f0$002fSD_ILS:433355/one
Llanos-Tejada F, Tamayo-Alarcón R. Bronquiectasias secundarias
a tuberculosis pulmonar en pacientes de un hospital general.
Rev Med Hered [Internet]. 2018;29(4):232-7. Disponible en:
http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1018-
X2018000400005
Zotes-Valdivia VH, Martínez-Arias MA, Mier-Odriozola JM, Morales-
Gómez J, Joffre-Aliaga A. Tratamiento quirúrgico del aspergiloma
pulmonar: experiencia de 10 años en el Instituto Nacional
de Enfermedades Respiratorias. Neumol Cir Torax [Internet].
;74(4):240-6. Disponible en: https://www.medigraphic.com/
pdfs/neumo/nt-2015/nt154b.pdf
Park SK, Lee CM, Heu JP, Song SD. A retrospective study for the
outcome of pulmonary resection in 49 patients with multidrugresistant
tuberculosis. Int J Tuberc Lung Dis [Internet]. 2002;6(2):143-
Disponible en: http://pubmed.ncbi.nlm.nih.gov/11931413/
Somocurcio JG, Sotomayor A, Shin S, Portilla S, Valcarcel M, Guerra
D, et al. Surgery for patients with drug-resistant tuberculosis: report
of 121 cases receiving community-based treatment in Lima, Peru.
Thorax [Internet]. 2007;62(5):416-21. Disponible en: https://doi.
org/10.1136/thx.2005.051961
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